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CS-W001157 4
Total: USD 88.00

3,5-Diiodobenzoic acid

  • CAS No. 19094-48-5

  • Cat. No. CS-0094290
  • Purity≥95%
  • MDL No.MFCD00463860
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3,5-Diiodobenzoic acid|CS-0094290

Structure of 19094-48-5

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Description

3,5-Diiodobenzoic acid features two iodine atoms positioned at the 3 and 5 ring positions, creating a highly electron-deficient aromatic core. This configuration enhances its utility in transition metal-catalyzed coupling reactions, particularly in Pd-mediated cross-couplings where halogen reactivity and stability are critical. The carboxylic acid group enables direct derivatization or incorporation into bioactive scaffolds, offering a robust handle for further functionalization.

Application

3,5-Diiodobenzoic acid serves as a valuable building block for the synthesis of iodinated aromatic scaffolds in medicinal chemistry and materials science. Its two ortho-directed iodine substituents enable sequential cross-coupling reactions, while the carboxylic acid group offers a handle for derivatization or conjugation. The compound exhibits excellent bench stability and facilitates efficient purification via recrystallization, making it well-suited for iterative synthetic workflows requiring high functional group tolerance and predictable reactivity.

General Information

  • CAS No. 19094-48-5
  • Cat. No. CS-0094290
  • Purity ≥95%
  • MDL No. MFCD00463860
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄I₂O₂
  • Molecular Weight 373.91
  • Synonym(s) Benzoic acid, 3,5-diiodo-
  • SMILES O=C(O)C1=CC(I)=CC(I)=C1

Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.594
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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