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Structure of 19094-48-5
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3,5-Diiodobenzoic acid features two iodine atoms positioned at the 3 and 5 ring positions, creating a highly electron-deficient aromatic core. This configuration enhances its utility in transition metal-catalyzed coupling reactions, particularly in Pd-mediated cross-couplings where halogen reactivity and stability are critical. The carboxylic acid group enables direct derivatization or incorporation into bioactive scaffolds, offering a robust handle for further functionalization.
3,5-Diiodobenzoic acid serves as a valuable building block for the synthesis of iodinated aromatic scaffolds in medicinal chemistry and materials science. Its two ortho-directed iodine substituents enable sequential cross-coupling reactions, while the carboxylic acid group offers a handle for derivatization or conjugation. The compound exhibits excellent bench stability and facilitates efficient purification via recrystallization, making it well-suited for iterative synthetic workflows requiring high functional group tolerance and predictable reactivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: