Lot numbers can be found on the outside label of a product:
2-(6-Chloro-1H-indol-3-yl)acetic acid
-
CAS No. 1912-44-3
- Cat. No. CS-W021419
- Purity≥98%
- MDL No.MFCD09751729
*For research and further manufacturing use only, not for direct human use.
Structure of 1912-44-3
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 1912-44-3
- Cat. No. CS-W021419
- Purity ≥98%
- MDL No. MFCD09751729
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₀H₈ClNO₂
- Molecular Weight 209.63
- Synonym(s) Nsc295295
- SMILES OC(=O)CC1=CNC2=CC(Cl)=CC=C12
Description
This indole-based acetic acid derivative features a chlorinated indole core linked to a carboxylic acid side chain, enabling integration into bioactive molecule scaffolds. The electron-deficient chloro substituent enhances metabolic stability and modulates electronic properties for targeted molecular design in medicinal chemistry applications.
Application
2-(6-Chloro-1H-indol-3-yl)acetic acid serves as a versatile building block for indole-based pharmaceutical intermediates, enabling efficient incorporation of the 6-chloroindole motif into bioactive scaffolds. Its carboxylic acid functionality facilitates direct coupling reactions and derivatization, while the chlorinated indole core provides enhanced metabolic stability and targeted receptor interactions. The compound exhibits good bench stability and is compatible with standard peptide coupling and heterocycle-forming protocols.
Synthesis
-
Route1
-
929005-85-6 - ~%
-
In-stock
1912-44-3
References
-
Lozano, Oscar; Blessley, George; Martinez Del Campo, Teresa; Thompson, Amber L.; Giuffredi, Guy T.; Bettati, Michela; Walker, Matthew; Borman, Richard; Gouverneur, Veronique Angewandte Chemie - International Edition, 2011 , vol. 50, # 35 p. 8105 - 8109
-
-
Route2
-
In-stock
17422-33-2 -
107-14-2 - ~%
-
In-stock
1912-44-3
References
-
Fox; Bullock Journal of the American Chemical Society, 1951 , vol. 73, p. 2756,2758
-
-
Route3
-
In-stock
17422-33-2
- ~%
-
In-stock
1912-44-3
References
-
Lozano, Oscar; Blessley, George; Martinez Del Campo, Teresa; Thompson, Amber L.; Giuffredi, Guy T.; Bettati, Michela; Walker, Matthew; Borman, Richard; Gouverneur, Veronique Angewandte Chemie - International Edition, 2011 , vol. 50, # 35 p. 8105 - 8109
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302
|
|
|
Precautionary Statements : P264-P270-P330-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 53.09
- LogP 2.4484
- H_Acceptors 1
- H_Donors 2
- Rotatable_Bonds 2
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 2-(6-Chloro-1H-indol-3-yl)acetic acid sigma2-(6-Chloro-1H-indol-3-yl)acetic acid manufacturer2-(6-Chloro-1H-indol-3-yl)acetic acid price2-(6-Chloro-1H-indol-3-yl)acetic acid structure2-(6-Chloro-1H-indol-3-yl)acetic acid SDSbuy 2-(6-Chloro-1H-indol-3-yl)acetic acid2-(6-Chloro-1H-indol-3-yl)acetic acid supplier2-(6-Chloro-1H-indol-3-yl)acetic acid uses2-(6-Chloro-1H-indol-3-yl)acetic acid molecular weightprice of 2-(6-Chloro-1H-indol-3-yl)acetic acid2-(6-Chloro-1H-indol-3-yl)acetic acid chemical name formula of 2-(6-Chloro-1H-indol-3-yl)acetic acid