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Structure of 1912-45-4
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2-(5-Chloro-1H-indol-3-yl)acetic acid features a chlorinated indole core linked to a carboxylic acid side chain, enabling direct incorporation into bioactive conjugates. The electron-deficient indole moiety enhances reactivity in coupling reactions, while the pendant acid group offers ready derivatization for peptide and small-molecule synthesis. This scaffold supports modular construction of targeted therapeutics and probes.
2-(5-Chloro-1H-indol-3-yl)acetic acid serves as a versatile building block for indole-based pharmaceutical intermediates, enabling efficient incorporation of the 5-chloroindole motif into bioactive scaffolds. Its carboxylic acid functionality facilitates direct coupling reactions and derivatization, while the chloro-substituted indole core provides enhanced metabolic stability and targeted receptor binding potential in medicinal chemistry applications. The compound exhibits good bench stability and is readily purified by standard chromatographic methods.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P233-P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501
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Lot numbers can be found on the outside label of a product: