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CS-W001157 4
Total: USD 88.00

5-Benzofurazancarboxylic acid

  • CAS No. 19155-88-5

  • Cat. No. CS-W008732
  • Purity≥98%
  • MDL No.MFCD00276977

*For research and further manufacturing use only, not for direct human use.

5-Benzofurazancarboxylic acid|CS-W008732

Structure of 19155-88-5

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General Information

  • CAS No. 19155-88-5
  • Cat. No. CS-W008732
  • Purity ≥98%
  • MDL No. MFCD00276977
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄N₂O₃
  • Molecular Weight 164.12
  • Synonym(s) Benzo[1,2,5]oxadiazole-5-carboxylic acid; Benzo[2,1,3]oxadiazole-5-carboxylic acid; Benzo[c][1,2,5]oxadiazole-5-carboxylic acid; 2,1,3-Benzoxadiazole-5-carboxylic acid
  • SMILES O=C(C1=CC2=NON=C2C=C1)O

Description

5-Benzofurazan carboxylic acid features a fused benzene-furazan core with a carboxylic acid group at the 5-position, delivering high stability and strong electron-withdrawing character. This arrangement enhances its utility in synthetic transformations requiring polarized functional groups, particularly in the construction of heterocyclic scaffolds for pharmaceutical and materials applications.

Application

5-Benzofurazancarboxylic acid serves as a versatile building block for heterocyclic synthesis, enabling direct functionalization at the carboxylic acid group for amide, ester, and acyl chloride derivatization. Its benzofurazan core provides enhanced stability and electron-deficient character, facilitating electrophilic substitution and serving as a key scaffold in bioactive molecule development. The compound exhibits good bench stability and is readily purified by recrystallization, supporting its use in medicinal chemistry and process-scale applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   76.22
  • LogP   0.921
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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