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Structure of 19181-77-2
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4-Oxo-3,4-dihydroquinazoline-8-carboxylic acid features a fused bicyclic core with a ketone at the 4-position and a carboxylic acid at the 8-position, delivering high polarity and hydrogen-bonding capacity. This scaffold integrates readily into medicinal chemistry campaigns targeting kinase inhibition and exhibits stability under standard bench conditions.
4-Oxo-3,4-dihydroquinazoline-8-carboxylic acid serves as a versatile scaffold for medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds. Its fused heterocyclic core exhibits moderate stability and facilitates diverse functionalization at the C8 position. The carboxylic acid group enables direct conjugation or salt formation, enhancing solubility and enabling further derivatization via standard amide coupling protocols. This compound functions reliably in standard peptide coupling and transition-metal-catalyzed transformations, offering consistent performance in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: