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CS-W001157 4
Total: USD 88.00

RuCl[(S,S)-Tsdpen](p-cymene)

  • CAS No. 192139-90-5

  • Cat. No. CS-0020093
  • Purity≥95%
  • MDL No.MFCD14155881

*For research and further manufacturing use only, not for direct human use.

RuCl[(S,S)-Tsdpen](p-cymene)|CS-0020093

Structure of 192139-90-5

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General Information

  • CAS No. 192139-90-5
  • Cat. No. CS-0020093
  • Purity ≥95%
  • MDL No. MFCD14155881
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₁H₃₅ClN₂O₂RuS
  • Molecular Weight 636.21
  • Synonym(s) [(η-6-Cymene)[(S,S)-1,2-diphenyl-N-tosyl-1,2-ethanediaminato]ruthenium] chloride]; [RuCl(TsDPEN)(η-6-cymene)]
  • SMILES Cc1ccc(C(C)C)cc1.CC2=CC=C(S(N3[Ru](Cl)[NH2][C@@H](C4=CC=CC=C4)[C@@H]3C5=CC=CC=C5)(=O)=O)C=C2

Application

RuCl[(S,S)-Tsdpen](p-cymene) serves as a robust, bench-stable catalyst for asymmetric hydrogenation reactions, enabling high enantioselectivity in the reduction of prochiral alkenes and imines. Its well-defined chiral environment, derived from the (S,S)-Tsdpen ligand, facilitates efficient stereocontrol in pharmaceutical intermediate synthesis. The p-cymene co-ligand enhances solubility and stability, supporting broad functional group tolerance and compatibility with standard laboratory workflows.

Synthesis

  • Route1

    References

    • WO2004/85414 A1, ; Page 13-14; 17-18 ;

Safety Information

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Computational Chemistry Data

  • TPSA   49.41
  • LogP   7.79194
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   5

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