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CS-W001157 4
Total: USD 88.00

(1-Methyl-1H-indol-5-yl)boronic acid

  • CAS No. 192182-55-1

  • Cat. No. CS-0035643
  • Molecule weight174.99
  • Purity≥95%
  • MDL No.MFCD03412070

*For research and further manufacturing use only, not for direct human use.

(1-Methyl-1H-indol-5-yl)boronic acid|CS-0035643

Structure of 192182-55-1

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General Information

  • CAS No. 192182-55-1
  • Cat. No. CS-0035643
  • Purity ≥95%
  • MDL No. MFCD03412070
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀BNO₂
  • Molecular Weight 174.99
  • Synonym(s) N-Methylindole-5-boronic acid
  • SMILES CN1C=CC2=C1C=CC(=C2)B(O)O

Description

This boronate moiety integrates readily into Suzuki-Miyaura cross-coupling reactions under standard conditions, delivering functionalized indole derivatives with high efficiency. The methyl substitution enhances solubility and stability, enabling reliable use in synthetic workflows without specialized handling.

Application

(1-Methyl-1H-indol-5-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation with aryl and heteroaryl halides. Its stability under ambient conditions, compatibility with diverse functional groups, and ease of purification make it well-suited for the synthesis of biologically relevant indole derivatives and pharmaceutical intermediates.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H315-H318-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   45.39
  • LogP   -0.1419
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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