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CS-W001157 4
Total: USD 88.00

(R)-1-Boc-piperazine-3-carboxylic acid

  • CAS No. 192330-11-3

  • Cat. No. CS-W009251
  • Purity≥97%
  • MDL No.MFCD02179099

*For research and further manufacturing use only, not for direct human use.

(R)-1-Boc-piperazine-3-carboxylic acid|CS-W009251

Structure of 192330-11-3

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General Information

  • CAS No. 192330-11-3
  • Cat. No. CS-W009251
  • Purity ≥97%
  • MDL No. MFCD02179099
  • Storage RT, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₈N₂O₄
  • Molecular Weight 230.26
  • Synonym(s) R-4-Boc-piperazine-2-carboxylic acid
  • SMILES O=C(OC(C)(C)C)N1C[C@@H](NCC1)C(O)=O

Description

(R)-1-Boc-piperazine-3-carboxylic acid features a stereochemically defined piperazine core with a Boc-protected amine and a carboxylic acid at the 3-position, enabling direct incorporation into peptide-like scaffolds. The protected functionality ensures stability during synthesis and purification, while the chiral center provides access to enantiopure analogs in medicinal chemistry campaigns.

Application

(R)-1-Boc-piperazine-3-carboxylic acid serves as a versatile chiral building block for the synthesis of bioactive molecules, particularly in medicinal chemistry and peptide conjugation. Its Boc-protected piperazine core enables facile deprotection and functionalization, while the carboxylic acid group supports efficient coupling reactions. The (R)-stereoisomer provides stereochemical control in target-directed synthesis, with excellent bench stability and compatibility with standard purification protocols.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H317-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   78.87
  • LogP   0.2799
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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