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Structure of 192927-69-8
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2,4-Difluoro-3-hydroxybenzaldehyde features a strategically positioned aldehyde group flanked by two fluorine atoms and a phenolic hydroxyl, enabling direct incorporation into bioactive scaffolds. The electron-withdrawing fluorines enhance electrophilicity at the carbonyl carbon, while the adjacent hydroxyl supports hydrogen bonding in target interactions. This combination delivers enhanced reactivity in coupling reactions and improved solubility under standard conditions.
2,4-Difluoro-3-hydroxybenzaldehyde serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to fluorinated aromatic scaffolds. Its hydroxyl and aldehyde functionalities offer orthogonal reactivity for coupling, derivatization, and heterocycle formation. The molecule exhibits good bench stability and facilitates straightforward purification, making it well-suited for multi-step synthetic sequences requiring functional group tolerance and predictable reactivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: