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CS-W001157 4
Total: USD 88.00

1-Boc-3-(Bromomethyl)piperidine

  • CAS No. 193629-39-9

  • Cat. No. CS-W019015
  • Purity≥96%
  • MDL No.MFCD04115539

*For research and further manufacturing use only, not for direct human use.

1-Boc-3-(Bromomethyl)piperidine|CS-W019015

Structure of 193629-39-9

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General Information

  • CAS No. 193629-39-9
  • Cat. No. CS-W019015
  • Purity ≥96%
  • MDL No. MFCD04115539
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₀BrNO₂
  • Molecular Weight 278.19
  • Synonym(s) Tert-butyl 3-(bromomethyl)piperidine-1-carboxylate
  • SMILES O=C(N1CC(CBr)CCC1)OC(C)(C)C

Description

1-Boc-3-(Bromomethyl)piperidine features a bromomethyl group appended to a piperidine ring, protected by a Boc moiety. This bifunctional scaffold enables direct incorporation into synthetic sequences, where the halide serves as a site for nucleophilic substitution and the protected amine facilitates downstream deprotection and functionalization under mild conditions.

Application

1-Boc-3-(Bromomethyl)piperidine serves as a versatile bifunctional building block in medicinal chemistry, enabling efficient incorporation of piperidine scaffolds into target molecules. The bromomethyl group facilitates nucleophilic substitution reactions, while the Boc-protected amine allows for orthogonal functionalization. This compound exhibits excellent bench stability and simplifies purification, making it well-suited for modular synthesis workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   29.54
  • LogP   3.0284
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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