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CS-W001157 4
Total: USD 88.00

(3S)-Fmoc-1-pyrrolidine-3-carboxylic acid

  • CAS No. 193693-66-2

  • Cat. No. CS-0207757
  • Purity≥95%
  • MDL No.MFCD04112695

*For research and further manufacturing use only, not for direct human use.

(3S)-Fmoc-1-pyrrolidine-3-carboxylic acid|CS-0207757

Structure of 193693-66-2

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General Information

  • CAS No. 193693-66-2
  • Cat. No. CS-0207757
  • Purity ≥95%
  • MDL No. MFCD04112695
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₀H₁₉NO₄
  • Molecular Weight 337.37
  • Synonym(s) None
  • SMILES C1=CC=C2C(=C1)C3=CC=CC=C3C2COC(=O)N4CC[C@@H](C4)C(=O)O

Description

This Fmoc-protected pyrrolidine derivative features a chiral (3S) configuration, enabling stereoselective incorporation into peptide chains. The bulky Fmoc group ensures efficient orthogonal protection, while the pyrrolidine ring imparts conformational rigidity, enhancing structural diversity in peptidomimetic design.

Application

(3S)-Fmoc-1-pyrrolidine-3-carboxylic acid serves as a stereochemically defined building block for the synthesis of peptidomimetics and constrained peptide architectures. The Fmoc group enables efficient solid-phase peptide synthesis, while the pyrrolidine ring provides a rigid, bioactive scaffold with favorable conformational control. Its stability under standard coupling conditions and compatibility with diverse functional groups facilitate reliable incorporation into complex molecular frameworks.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   66.84
  • LogP   3.342
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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