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Structure of 195515-48-1
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This chiral bisoxazole features a rigid pentane-3,3-diyl spacer linking two 4-phenyl-4,5-dihydrooxazole units, enabling precise spatial control in asymmetric synthesis. The (4R,4'R) stereochemistry ensures high diastereoselectivity in cyclization reactions, while the phenyl groups enhance π-stacking interactions. Bench-stable and moisture-tolerant, it integrates seamlessly into catalytic systems requiring defined three-dimensional architecture.
(4R,4'R)-2,2'-(Pentane-3,3-diyl)bis(4-phenyl-4,5-dihydrooxazole) serves as a chiral bis-oxazoline scaffold with high bench stability and excellent functional group tolerance. It functions as a versatile ligand in asymmetric catalysis, enabling efficient enantioselective transformations through robust metal coordination. Its rigid, C2-symmetric structure facilitates reproducible stereocontrol in cross-coupling and cycloaddition reactions, making it a practical choice for scalable synthetic applications in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: