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CS-W001157 4
Total: USD 88.00

1-(Tert-butyl) 2-methyl (2S,4S)-4-methyl-5-oxopyrrolidine-1,2-dicarboxylate

  • CAS No. 196394-48-6

  • Cat. No. CS-0495982
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-(Tert-butyl) 2-methyl (2S,4S)-4-methyl-5-oxopyrrolidine-1,2-dicarboxylate|CS-0495982

Structure of 196394-48-6

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General Information

  • CAS No. 196394-48-6
  • Cat. No. CS-0495982
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₉NO₅
  • Molecular Weight 257.28
  • Synonym(s) Methyl (2S,4S)-1-(tert-butoxycarbonyl)-4-methylpyroglutamate
  • SMILES COC(=O)[C@@H]1C[C@H](C)C(=O)N1C(=O)OC(C)(C)C

Synthesis

  • Route1
    • null|null
      219844-08-3
    • ~99%
    • 1-(Tert-butyl) 2-methyl (2S,4S)-4-methyl-5-oxopyrrolidine-1,2-dicarboxylate|CS-0495982
      196394-48-6

    References

    • The Procter and Gamble Company Patent: US2007/232804 A1, 2007 ; Location in patent: Page/Page column 4; 5 ;
  • Route2
    • null|null
      219844-08-3
    • ~%
    • 1-tert-Butyl 2-methyl (2S,4R)-4-methyl-5-oxopyrrolidine-1,2-dicarboxylate|CS-0055516
      196394-49-7
    • 1-(Tert-butyl) 2-methyl (2S,4S)-4-methyl-5-oxopyrrolidine-1,2-dicarboxylate|CS-0495982
      196394-48-6

    References

    • US2007/232650 A1, ; Page/Page column 5 ;
  • Route3
    • In-stock
      Boc-L-Pyroglutamic acid methyl ester|CS-W003361
      108963-96-8
    • null|null
      74-88-4
    • ~%
    • 1-tert-Butyl 2-methyl (2S,4R)-4-methyl-5-oxopyrrolidine-1,2-dicarboxylate|CS-0055516
      196394-49-7
    • 1-(Tert-butyl) 2-methyl (2S,4S)-4-methyl-5-oxopyrrolidine-1,2-dicarboxylate|CS-0495982
      196394-48-6

    References

    • WO2012/148775 A1, ; Page/Page column 85 ; WO 2012/148775 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   72.91
  • LogP   1.3315
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   1

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