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CS-W001157 4
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3-Bromo-5-chloro-2-hydroxybenzaldehyde

  • CAS No. 19652-32-5

  • Cat. No. CS-W010326
  • Purity≥98%
  • MDL No.MFCD00051690

*For research and further manufacturing use only, not for direct human use.

3-Bromo-5-chloro-2-hydroxybenzaldehyde|CS-W010326

Structure of 19652-32-5

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General Information

  • CAS No. 19652-32-5
  • Cat. No. CS-W010326
  • Purity ≥98%
  • MDL No. MFCD00051690
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄BrClO₂
  • Molecular Weight 235.46
  • Synonym(s) 3-Bromo-5-chlorosalicylaldehyde; 3-Bromo-5-chloro-2-hydroxybenzaldehyde
  • SMILES O=CC1=CC(Cl)=CC(Br)=C1O

Description

N-Fmoc-L-alanine is potentially useful for proteomics studies and solid phase peptide synthesis techniques. Alanine is one of the simplest amino acids - a methyl group as the side chain. This small side chain confers a high degree of flexibility when incorporated into a polypeptide chain. The Fmoc group is typically removed with a base such as pyridine - an orthogonal de-protection strategy to the acid labilie Boc group.

Application

3-Bromo-5-chloro-2-hydroxybenzaldehyde serves as a versatile building block for the synthesis of substituted benzene derivatives and heterocyclic scaffolds. Its strategic placement of bromo, chloro, and hydroxy groups enables selective functionalization via cross-coupling, electrophilic substitution, or protection strategies. The aldehyde functionality facilitates condensation reactions, while the phenolic hydroxyl group offers opportunities for derivatization or metal coordination. Bench-stable and compatible with standard purification methods, it supports efficient workflow integration in medicinal chemistry and materials science applications.

Synthesis

  • Route1

    References

    • GLAXO GROUP LIMITED Patent: WO2008/98978 A2, 2008 ; Location in patent: Page/Page column 37-38 ; WO 2008/098978 A2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.6206
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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