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6,7-Dihydro-5H-pyrrolo[1,2-a]imidazole-6-carboxylic acid hydrochloride

  • CAS No. 1965310-16-0

  • Cat. No. CS-0060097
  • Molecule weight188.61
  • Purity≥96%
  • MDL No.MFCD30181971

*For research and further manufacturing use only, not for direct human use.

6,7-Dihydro-5H-pyrrolo[1,2-a]imidazole-6-carboxylic acid hydrochloride|CS-0060097

Structure of 1965310-16-0

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General Information

  • CAS No. 1965310-16-0
  • Cat. No. CS-0060097
  • Purity ≥96%
  • MDL No. MFCD30181971
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉ClN₂O₂
  • Molecular Weight 188.61
  • Synonym(s) 6,7-DIHYDRO-5H-PYRROLO[1,2-A]IMIDAZOLE-6-CARBOXYLIC ACID HCL
  • SMILES C1=2N(CC(C1)C(O)=O)C=CN2.Cl

Description

6,7-Dihydro-5H-pyrrolo[1,2-a]imidazole-6-carboxylic acid hydrochloride features a fused heterocyclic core with a carboxylic acid group and protonated imidazole nitrogen, enhancing solubility and stability. This bench-stable derivative integrates readily into peptide couplings and bioconjugation workflows, offering a rigid, electron-rich scaffold for medicinal chemistry applications.

Application

6,7-Dihydro-5H-pyrrolo[1,2-a]imidazole-6-carboxylic acid hydrochloride serves as a versatile heterocyclic building block for medicinal chemistry applications. Its carboxylic acid functionality enables direct amidation, esterification, and coupling reactions under standard conditions. The dihydroimidazole core exhibits favorable bench stability and functional group tolerance, facilitating integration into diverse synthetic sequences for API development and scaffold diversification.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   55.12
  • LogP   0.5618
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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