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(R)-6,7-Dihydro-5H-pyrrolo[1,2-a]imidazol-6-ol

  • CAS No. 196862-45-0

  • Cat. No. CS-0135889
  • Purity≥97%
  • MDL No.MFCD22543843

*For research and further manufacturing use only, not for direct human use.

(R)-6,7-Dihydro-5H-pyrrolo[1,2-a]imidazol-6-ol|CS-0135889

Structure of 196862-45-0

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General Information

  • CAS No. 196862-45-0
  • Cat. No. CS-0135889
  • Purity ≥97%
  • MDL No. MFCD22543843
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₈N₂O
  • Molecular Weight 124.14
  • Synonym(s) (6R)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-6-ol
  • SMILES O[C@@H]1CC2=NC=CN2C1

Description

(R)-6,7-Dihydro-5H-pyrrolo[1,2-a]imidazol-6-ol is a stereochemically defined heterocyclic scaffold featuring a fused pyrroloimidazole core with a hydroxyl group at the 6-position. This bench-stable, electron-rich framework integrates readily into complex molecular architectures and serves as a key building block in medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds.

Application

(R)-6,7-Dihydro-5H-pyrrolo[1,2-a]imidazol-6-ol serves as a versatile heterocyclic building block for medicinal chemistry applications, enabling efficient access to pyrroloimidazole scaffolds. Its well-defined stereochemistry and bench-stable nature facilitate reliable coupling reactions and functionalization at the C6 position. The compound exhibits good solubility and compatibility with standard synthetic protocols, supporting its use in modular synthesis of bioactive molecules.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   38.05
  • LogP   -0.1999
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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