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Structure of 197223-39-5
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This boronate moiety features a sterically shielded aryl core, enhancing stability and resistance to protodeboronation. The ortho-tert-butyl groups create a protective environment around the boronic acid functional group, enabling reliable performance in Suzuki-Miyaura couplings under standard conditions. Ideal for late-stage functionalization and complex molecule synthesis.
(3,5-Di-tert-butylphenyl)boronic acid serves as a sterically hindered arylboronic acid that facilitates Suzuki-Miyaura cross-coupling reactions with high functional group tolerance and improved stability under ambient conditions. Its bulky tert-butyl groups enhance oxidative stability and reduce protodeboronation, enabling reliable coupling in complex molecule synthesis. The compound is particularly valuable for constructing sterically congested biaryl scaffolds in pharmaceutical and materials chemistry.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: