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Structure of 197239-54-6
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3-(3-Fluorophenyl)prop-2-yn-1-ol features a conjugated alkyne tethered to a fluorinated phenyl ring, enabling efficient coupling in transition-metal-catalyzed transformations. The terminal alkyne and primary alcohol functionalities facilitate diverse downstream modifications. This compound exhibits excellent stability under standard conditions and integrates readily into complex molecular architectures.
3-(3-Fluorophenyl)prop-2-yn-1-ol serves as a versatile synthetic building block for the construction of functionalized aryl alkynes, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions. Its terminal alkyne functionality exhibits high reactivity in click chemistry applications, while the ortho-fluorophenyl moiety provides enhanced metabolic stability and favorable electronic properties. The molecule demonstrates excellent bench stability and compatibility with common protecting groups, facilitating straightforward purification and integration into complex molecular architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: