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Structure of 197376-41-3
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Ethyl 2-(3-bromopyridin-2-yl)acetate features a pyridine ring flanked by a bromine atom and an ester-functionalized acetyl side chain, enabling direct incorporation into cross-coupling reactions. The electron-deficient pyridine moiety enhances reactivity in palladium-catalyzed transformations, while the ethyl ester group offers stability and ease of manipulation under standard conditions. This compound serves as a key intermediate for synthesizing bioactive heterocycles and pharmaceutical scaffolds.
Ethyl 2-(3-bromopyridin-2-yl)acetate serves as a versatile building block for constructing pyridine-based scaffolds in medicinal chemistry and catalytic cross-coupling reactions. The bromo group enables reliable Suzuki, Stille, or Negishi coupling, while the ester functionality offers compatibility with reduction, hydrolysis, and further functionalization. Bench-stable and readily purified by column chromatography, it facilitates efficient access to biologically relevant heterocycles and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: