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Structure of 1975-52-6
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5-Nitro-2-methylbenzoic acid features a para-nitro group flanked by a methyl substituent and carboxylic acid functionality, enabling selective conjugation in synthetic routes. This electron-deficient aromatic core enhances reactivity in nucleophilic substitution and coupling reactions, offering robust stability under standard conditions.
5-Nitro-2-methylbenzoic acid serves as a versatile building block in synthetic organic chemistry, enabling the construction of substituted benzoic acid derivatives and heterocyclic scaffolds. Its ortho-methyl and para-nitro substituents provide defined electronic and steric control, facilitating selective functionalization. The carboxylic acid group offers direct handle for amidation, esterification, or coupling reactions, while the nitro group permits reduction to an amine under standard conditions. Bench-stable and readily purified by recrystallization, it functions effectively in both medicinal chemistry lead optimization and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H317
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Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P362+P364-P501
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Lot numbers can be found on the outside label of a product: