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Structure of 19752-57-9
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1,3-Dibromo-5-iodobenzene features a uniquely halogenated aromatic core with bromine and iodine substituents positioned at meta and para relative to one another. This electron-deficient scaffold enables direct coupling in cross-coupling reactions, offering high functional group tolerance and stability under standard conditions. The strategic placement of heavy halogens facilitates sequential transformations in synthetic sequences.
1,3-Dibromo-5-iodobenzene serves as a versatile halogenated aromatic building block for palladium-catalyzed cross-coupling reactions. Its orthogonal halogen reactivity enables sequential functionalization, with bromine and iodine sites participating in distinct coupling events under selective catalytic conditions. The compound exhibits excellent bench stability and facilitates efficient synthesis of complex biaryl architectures, particularly in the construction of substituted heterocycles and pharmaceutical scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: