2-Bromo-3-nitropyridine

Name: 2-Bromo-3-nitropyridine
Brand: ChemScene
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CAS No. 19755-53-4
Cat. No. CS-W015483
Purity≥98%
MDL No.MFCD00955613

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 19755-53-4

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Description

2-Bromo-3-nitropyridine features a strategically positioned bromine and nitro group on the pyridine ring, enabling direct functionalization in cross-coupling and nucleophilic substitution reactions. The electron-deficient heterocycle enhances reactivity toward palladium-catalyzed transformations, while maintaining stability under standard bench conditions.

Application

2-Bromo-3-nitropyridine serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its stable bromine functionality. The nitro group provides a handle for selective reduction and further functionalization, while the pyridine core offers inherent polarity and coordination capability. Its bench stability and compatibility with standard reaction conditions facilitate efficient access to substituted pyridine scaffolds relevant to medicinal chemistry and agrochemical development.

General Information

CAS No. 19755-53-4
Cat. No. CS-W015483
Purity ≥98%
MDL No. MFCD00955613
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₃BrN₂O₂
Molecular Weight 202.99
Synonym(s) 2-bromo-3-nitro pyridine; 2-Bromo-3-nitropyridine
SMILES O=[N+](C1=CC=CN=C1Br)[O-]

Computational Chemistry Data

TPSA 56.03
LogP 1.7523
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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2-Bromo-3-nitropyridine

CAS No. 19755-53-4

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