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Structure of 1979-36-8
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1-(2,5-Difluorophenyl)ethanone features a fluorinated aromatic ring paired with a reactive ketone group, enabling direct incorporation into pharmaceutical intermediates. The ortho- and para-fluoro substituents enhance metabolic stability and influence electronic properties for targeted synthetic transformations. This bench-stable compound serves as a key building block in medicinal chemistry campaigns requiring electron-deficient aryl ketones.
1-(2,5-Difluorophenyl)ethanone serves as a versatile aryl ketone building block for medicinal chemistry and materials synthesis. Its difluorophenyl moiety enhances metabolic stability and modulates electronic properties, while the acetyl group enables standard transformations including nucleophilic addition, reduction, and coupling reactions. Bench-stable and readily purified by recrystallization, it functions effectively in Friedel-Crafts acylation, Grignard additions, and transition-metal-catalyzed cross-couplings.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352
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Lot numbers can be found on the outside label of a product: