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Structure of 19808-30-1
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5-Bromopyrimidin-4(3H)-one features a bromine substituent at the 5-position of a pyrimidinone core, enabling selective functionalization in synthetic pathways. The carbonyl group at C4 imparts reactivity for nucleophilic substitution, while the electron-deficient ring system facilitates coupling reactions under mild conditions. This bench-stable heterocycle serves as a key intermediate in medicinal chemistry and agrochemical synthesis.
5-Bromopyrimidin-4(3H)-one serves as a versatile building block in medicinal chemistry, enabling site-specific functionalization via cross-coupling reactions. Its bromine substituent facilitates palladium-catalyzed transformations, while the pyrimidinone core provides a stable, hydrogen-bonding scaffold for target engagement. The compound exhibits excellent bench stability and compatibility with diverse reaction conditions, simplifying purification and scale-up.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: