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CS-W001157 4
Total: USD 88.00

3-Methyl-2-oxazolidone

  • CAS No. 19836-78-3

  • Cat. No. CS-W016647
  • Molecule weight101.11
  • Purity≥98%
  • MDL No.MFCD00009759

*For research and further manufacturing use only, not for direct human use.

3-Methyl-2-oxazolidone|CS-W016647

Structure of 19836-78-3

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General Information

  • CAS No. 19836-78-3
  • Cat. No. CS-W016647
  • Purity ≥98%
  • MDL No. MFCD00009759
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇NO₂
  • Molecular Weight 101.11
  • Synonym(s) Methyloxazolidone
  • SMILES O=C1OCCN1C

Application

3-Methyl-2-oxazolidone serves as a stable, bench-friendly synthon for the construction of nitrogen-containing heterocycles and chiral auxiliaries. Its inherent electrophilic carbonyl and amide functionality enables reliable Michael additions, nucleophilic acyl substitutions, and cycloaddition reactions. The molecule exhibits excellent functional group tolerance and facilitates straightforward purification, making it a practical choice for medicinal chemistry campaigns and process-scale synthesis.

Synthesis

  • Route1
    • null|null
      124-38-9
    • null|null
      107-06-2
    • null|null
      74-89-5
    • ~93%
    • In-stock
      3-Methyl-2-oxazolidone|CS-W016647
      19836-78-3

    References

    • US2005/154200 A1, ; Page/Page column 4 ;
  • Route2
    • In-stock
      2-(Methylamino)ethanol|CS-W008875
      109-83-1
    • null|null
      201230-82-2
    • ~78%
    • In-stock
      3-Methyl-2-oxazolidone|CS-W016647
      19836-78-3
    • null|null
      7624-61-5

    References

    • Journal of Organic Chemistry, , vol. 51, # 15 p. 2977 - 2981
  • Route3
    • In-stock
      2-(Methylamino)ethanol|CS-W008875
      109-83-1
    • null|null
      201230-82-2
    • ~86%
    • In-stock
      3-Methyl-2-oxazolidone|CS-W016647
      19836-78-3

    References

    • Journal of Organic Chemistry, , vol. 48, # 22 p. 3901 - 3908

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P233-P260-P261-P264-P271-P280-P302+P352-P304+P340-P340-P362-P403-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.54
  • LogP   0.0684
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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