Fmoc-D-Chg-OH

Name: Fmoc-D-Chg-OH
Brand: ChemScene
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CAS No. 198543-96-3
Cat. No. CS-0149819
Purity≥98%
MDL No.MFCD00190877

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 198543-96-3

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Description

Fmoc-D-Chg-OH is a bench-stable, moisture-tolerant amino acid derivative featuring a D-configured choline moiety. This polar, zwitterionic side chain enhances solubility in aqueous and mixed solvents while maintaining compatibility with standard peptide synthesis protocols. The Fmoc group enables efficient N-terminal protection, streamlining incorporation into complex sequences.

Application

Fmoc-D-Chg-OH serves as a key building block in peptide synthesis, enabling the incorporation of D-3-chloro-homoglutamine residues with high stability and ease of purification. The Fmoc group provides robust protection for the α-amino function, facilitating efficient coupling and orthogonal deprotection. Its chlorinated side chain offers enhanced metabolic stability and can serve as a site for downstream functionalization, making it valuable in the construction of bioactive peptides and peptidomimetics.

General Information

CAS No. 198543-96-3
Cat. No. CS-0149819
Purity ≥98%
MDL No. MFCD00190877
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₃H₂₅NO₄
Molecular Weight 379.45
Synonym(s) (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-cyclohexylacetic acid
SMILES O=C(O)[C@H](NC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)C4CCCCC4

Computational Chemistry Data

TPSA 75.63
LogP 4.5586
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 5

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Alanine and derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

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Fmoc-D-Chg-OH

CAS No. 198543-96-3

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