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CS-W001157 4
Total: USD 88.00

(S)-2-Amino-3-(3-nitrophenyl)propanoic acid

  • CAS No. 19883-74-0

  • Cat. No. CS-0042825
  • Purity≥96%
  • MDL No.MFCD01860661

*For research and further manufacturing use only, not for direct human use.

(S)-2-Amino-3-(3-nitrophenyl)propanoic acid|CS-0042825

Structure of 19883-74-0

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General Information

  • CAS No. 19883-74-0
  • Cat. No. CS-0042825
  • Purity ≥96%
  • MDL No. MFCD01860661
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀N₂O₄
  • Molecular Weight 210.19
  • Synonym(s) None
  • SMILES O=C(O)[C@@H](N)CC1=CC=CC([N+]([O-])=O)=C1

Description

(S)-2-Amino-3-(3-nitrophenyl)propanoic acid is a chiral building block featuring a para-nitro-substituted phenyl group and a stereodefined amino acid backbone. This configuration enables direct incorporation into peptide sequences, where the electron-deficient aromatic ring enhances binding affinity in target-directed conjugations. The compound exhibits bench-stable handling characteristics and compatibility with standard coupling protocols in synthetic biology workflows.

Application

(S)-2-Amino-3-(3-nitrophenyl)propanoic acid serves as a valuable chiral building block for the synthesis of biologically relevant heterocycles and peptide-like scaffolds. Its well-defined stereochemistry and compatibility with standard coupling reactions enable efficient access to pharmaceutically active intermediates. The ortho-nitrophenyl group provides a handle for selective transformations, while the amino and carboxylic acid functionalities offer versatility in derivatization. Bench-stable and readily purified, it functions effectively in both small-scale medicinal chemistry campaigns and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   106.46
  • LogP   0.5492
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   4

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