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Structure of 199678-12-1
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4-Pyrimidin-2-yl-benzoic acid features a rigid, planar architecture integrating a pyrimidine ring with a benzoic acid moiety. This arrangement enables strong π–π stacking and directional hydrogen bonding, enhancing its utility in crystal engineering and supramolecular assembly. The carboxylic acid group facilitates derivatization under standard coupling conditions.
4-Pyrimidin-2-yl-benzoic acid serves as a versatile building block for constructing biologically active heterocyclic scaffolds. Its dual aromatic systems enable efficient coupling reactions, while the carboxylic acid group facilitates direct derivatization or amide formation under standard conditions. The molecule exhibits good bench stability and clean purification profiles, making it well-suited for medicinal chemistry campaigns requiring modular scaffold assembly.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: