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CS-W001157 4
Total: USD 88.00

(4-(Hydroxymethyl)piperidin-1-yl)(phenyl)methanone Efinaconazole Impurity

  • CAS No. 19980-00-8

  • Cat. No. CS-0460253
  • Purity≥98%
  • MDL No.MFCD08694474

*For research and further manufacturing use only, not for direct human use.

(4-(Hydroxymethyl)piperidin-1-yl)(phenyl)methanone Efinaconazole Impurity|CS-0460253

Structure of 19980-00-8

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General Information

  • CAS No. 19980-00-8
  • Cat. No. CS-0460253
  • Purity ≥98%
  • MDL No. MFCD08694474
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₇NO₂
  • Molecular Weight 219.28
  • Synonym(s) (4-(Hydroxymethyl)piperidin-1-yl)(phenyl)methanone
  • SMILES O=C(N1CCC(CO)CC1)C2=CC=CC=C2

Synthesis

  • Route1

    References

    • AXYS PHARMACEUTICALS, INC. Patent: WO2006/69096 A1, 2006 ; Location in patent: Page/Page column 96 ; WO 2006/069096 A1
  • Route2
    • ethyl 1-benzoylpiperidine-4-carboxylate|CS-W000135
      136081-74-8
    • ~67%
    • (4-(Hydroxymethyl)piperidin-1-yl)(phenyl)methanone Efinaconazole Impurity|CS-0460253
      19980-00-8

    References

    • Barbe, Guillaume; Charette, Andre B. Journal of the American Chemical Society, 2008 , vol. 130, # 1 p. 18 - 19
  • Route3

    References

    • Merck and Co., Inc. Patent: US6248755 B1, 2001 ; US 6248755 B1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319
Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.54
  • LogP   1.5311
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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