6-Bromo-3-fluoroimidazo[1,2-a]pyridine

Name: 6-Bromo-3-fluoroimidazo[1,2-a]pyridine
Brand: ChemScene
Availability: InStock
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CAS No. 2001563-56-8
Cat. No. CS-0092213
Purity≥97%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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6-Bromo-3-fluoroimidazo[1,2-a]pyridine|CS-0092213

Structure of 2001563-56-8

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Description

6-Bromo-3-fluoroimidazo[1,2-a]pyridine features a fused heterocyclic core with complementary halogen substituents enabling direct functionalization. The bromine at the 6-position and fluorine at the 3-position offer orthogonal reactivity for palladium-catalyzed cross-coupling and nucleophilic substitution. This electron-deficient scaffold integrates readily into bioactive molecule architectures, particularly in kinase inhibitor development and medicinal chemistry libraries.

Application

6-Bromo-3-fluoroimidazo[1,2-a]pyridine serves as a versatile heterocyclic building block for medicinal chemistry and materials science. Its dual halogenation pattern enables palladium-catalyzed cross-coupling reactions with high regioselectivity, facilitating the construction of complex imidazopyridine scaffolds. The molecule exhibits excellent bench stability, ease of purification, and tolerance to a range of functional groups, making it well-suited for iterative synthesis in API development and small-molecule library generation.

General Information

CAS No. 2001563-56-8
Cat. No. CS-0092213
Purity ≥97%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₄BrFN₂
Molecular Weight 215.02
Synonym(s) None
SMILES BrC1=CN2C(C=C1)=NC=C2F

Computational Chemistry Data

TPSA 17.3
LogP 2.2359
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 0

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Imidazole compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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6-Bromo-3-fluoroimidazo[1,2-a]pyridine

CAS No. 2001563-56-8

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