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CS-W001157 4
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3,3-Diphenylpropan-1-ol

  • CAS No. 20017-67-8

  • Cat. No. CS-W009323
  • Purity≥95%
  • MDL No.MFCD00002930

*For research and further manufacturing use only, not for direct human use.

3,3-Diphenylpropan-1-ol|CS-W009323

Structure of 20017-67-8

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General Information

  • CAS No. 20017-67-8
  • Cat. No. CS-W009323
  • Purity ≥95%
  • MDL No. MFCD00002930
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₆O
  • Molecular Weight 212.29
  • Synonym(s) 3,3-Diphenylpropanol
  • SMILES OCCC(C1=CC=CC=C1)C1=CC=CC=C1

Description

3,3-Diphenylpropan-1-ol features a benzhydryl-like core with a primary alcohol handle, offering enhanced stability and solubility in polar organic media. This bench-stable scaffold integrates readily into synthetic sequences requiring rigid, electron-rich aryl linkages, enabling efficient access to functionalized building blocks for medicinal chemistry and materials applications.

Application

3,3-Diphenylpropan-1-ol serves as a valuable building block in synthetic organic chemistry, enabling the construction of biaryl-containing scaffolds and functionalized aliphatic chains. Its benzylic alcohol functionality facilitates oxidation to the corresponding carboxylic acid or conversion to esters and ethers, while the two phenyl groups confer structural rigidity and enhanced lipophilicity. The compound exhibits good bench stability and is compatible with standard reaction conditions, making it suitable for use in medicinal chemistry lead optimization and materials science applications.

Synthesis

  • Route1

    References

    • Leclerc, Gerard; Decker, Nicole; Schwartz, Jean Journal of Medicinal Chemistry, 1982 , vol. 25, # 6 p. 709 - 714
  • Route2
    • null|null
      23084-88-0
    • ~62%
    • In-stock
      3,3-Diphenylpropan-1-ol|CS-W009323
      20017-67-8

    References

    • Harada, Nari-Aki; Nishikata, Takashi; Nagashima, Hideo Tetrahedron, 2012 , vol. 68, # 15 p. 3243 - 3252
  • Route3
    • Ethyl 3,3-diphenylpropanoate|CS-0365796
      7476-18-8
    • ~%
    • In-stock
      3,3-Diphenylpropan-1-ol|CS-W009323
      20017-67-8

    References

    • Chemicke Listy, , vol. 45, p. 20,22 Chem.Abstr., , p. 8997

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   3.2009
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   4

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