6-Bromo-2-hydroxy-3-methoxybenzaldehyde

Name: 6-Bromo-2-hydroxy-3-methoxybenzaldehyde
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 20035-41-0
Cat. No. CS-7790
Purity≥98%
MDL No.MFCD00046152

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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6-Bromo-2-hydroxy-3-methoxybenzaldehyde|CS-7790

Structure of 20035-41-0

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Description

6-Bromo-2-hydroxy-3-methoxybenzaldehyde features a brominated, hydroxylated, and methoxylated aromatic scaffold that enables direct functionalization in cross-coupling and electrophilic substitution reactions. The aldehyde group provides a handle for derivatization, while the ortho-hydroxy and meta-methoxy substituents stabilize the molecule under standard conditions. This compound serves as a key building block for bioactive heterocycles and natural product analogs.

Application

6-Bromo-2-hydroxy-3-methoxybenzaldehyde serves as a versatile building block in the synthesis of bioactive heterocycles and functionalized aromatic scaffolds. The molecule combines bromine for late-stage coupling, phenolic hydroxyl for derivatization or metal complexation, and methoxy and aldehyde groups enabling orthogonal transformations. Its bench-stable nature and compatibility with standard cross-coupling, oxidation, and cyclization protocols make it well-suited for medicinal chemistry and materials synthesis workflows.

General Information

CAS No. 20035-41-0
Cat. No. CS-7790
Purity ≥98%
MDL No. MFCD00046152
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₇BrO₃
Molecular Weight 231.04
Synonym(s) NSC95682
SMILES O=CC1=C(C(OC)=CC=C1Br)O

Computational Chemistry Data

TPSA 46.53
LogP 1.9758
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P233-P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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Other Classifications

Building Blocks Functional Group Phenol

Building Blocks Functional Group Ether

Building Blocks Functional Group Aldehyde

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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6-Bromo-2-hydroxy-3-methoxybenzaldehyde

CAS No. 20035-41-0

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