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Structure of 202001-00-1
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2-(3-Chloro-5-fluorophenyl)acetic acid features a benzene ring bearing ortho-chloro and meta-fluoro substituents, delivering enhanced electron-withdrawing character. This configuration supports robust coupling efficiency in peptide synthesis and pharmaceutical intermediates, offering improved solubility and stability under standard conditions.
2-(3-Chloro-5-fluorophenyl)acetic acid serves as a valuable building block for pharmaceutical intermediates, enabling efficient construction of biologically relevant heterocyclic scaffolds. Its ortho-halogenated aryl core provides excellent functional group tolerance and facilitates palladium-catalyzed cross-coupling reactions. The carboxylic acid functionality offers straightforward derivatization options, including amide formation and esterification, while the compound exhibits good bench stability and ease of purification—making it well-suited for iterative synthesis workflows in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: