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Structure of 20249-16-5
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3-Oxocyclobutane-1-carbonitrile is a strained cyclic ketonitrile featuring a reactive carbonyl group and a nitrile functionality within a four-membered ring. This configuration enables participation in cycloadditions and nucleophilic additions, facilitating access to complex heterocyclic scaffolds. The molecule exhibits enhanced reactivity due to ring strain and electronic polarization between the carbonyl and nitrile moieties.
3-Oxocyclobutane-1-carbonitrile serves as a versatile synthetic building block for strained ring systems and heterocyclic scaffolds. Its dual functionality—ketone and nitrile groups—enables selective transformations, including nucleophilic additions and cyclizations, under mild conditions. The molecule exhibits good bench stability and facilitates efficient purification, making it well-suited for iterative synthesis in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS06,GHS09
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Signal Word : Danger
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UN#: 3077
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Class : 9
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Packing Group : Ⅲ
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Hazard Statements : H301+H331-H410
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Precautionary Statements : P261-P264-P270-P271-P273-P304+P340-P330-P391-P405-P501
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Lot numbers can be found on the outside label of a product: