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Structure of 202865-59-6
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1-Bromo-3,5-difluoro-2-methoxybenzene features a trifluorinated aromatic core with strategically positioned bromo and methoxy substituents, enabling selective cross-coupling reactions. The electron-deficient ring enhances reactivity in palladium-catalyzed transformations, while the methoxy group improves solubility and stability under standard conditions. This scaffold delivers precise structural control for advanced pharmaceutical intermediates and functional materials.
1-Bromo-3,5-difluoro-2-methoxybenzene serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling palladium-catalyzed cross-coupling reactions due to its ortho-bromine functionality. The difluoro substitution enhances metabolic stability and modulates electronic properties, while the methoxy group provides a handle for further derivatization. Its bench-stable nature and compatibility with diverse reaction conditions make it well-suited for iterative synthesis of complex heterocyclic scaffolds and functionalized aromatic systems.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: