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CS-W001157 4
Total: USD 88.00

2,2,2-Trifluoro-1-(4-(4-bromobenzoyl)piperidin-1-yl)ethanone

  • CAS No. 203186-01-0

  • Cat. No. CS-W001495
  • Purity≥96%
  • MDL No.MFCD12912608

*For research and further manufacturing use only, not for direct human use.

2,2,2-Trifluoro-1-(4-(4-bromobenzoyl)piperidin-1-yl)ethanone|CS-W001495

Structure of 203186-01-0

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General Information

  • CAS No. 203186-01-0
  • Cat. No. CS-W001495
  • Purity ≥96%
  • MDL No. MFCD12912608
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₃BrF₃NO₂
  • Molecular Weight 364.16
  • Synonym(s) 2,2,2-Trifluoro-1-(4-(4-bromobenzoyl)-piperidin-1-yl)ethanone
  • SMILES BrC1=CC=C(C(C2CCN(C(C(F)(F)F)=O)CC2)=O)C=C1

Synthesis

  • Route1
    • null|null
      108-86-1
    • null|null
      126501-71-1
    • ~%
    • 2,2,2-Trifluoro-1-(4-(4-bromobenzoyl)piperidin-1-yl)ethanone|CS-W001495
      203186-01-0

    References

    • SCHERING CORPORATION Patent: EP1175402 B1, 2005 ; Location in patent: Page/Page column 30 ;
  • Route2
    • Piperidine-4-carboxylic acid Avatrombopag Impurity|CS-0377512
      498-94-2
    • ~%
    • 2,2,2-Trifluoro-1-(4-(4-bromobenzoyl)piperidin-1-yl)ethanone|CS-W001495
      203186-01-0

    References

    • Palani; Shapiro; Clader; Greenlee; Cox; Strizki; Endres; Baroudy Journal of Medicinal Chemistry, 2001 , vol. 44, # 21 p. 3339 - 3342
  • Route3

    References

    • Palani; Shapiro; Clader; Greenlee; Cox; Strizki; Endres; Baroudy Journal of Medicinal Chemistry, 2001 , vol. 44, # 21 p. 3339 - 3342

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   37.38
  • LogP   3.4327
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

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