3,4-Dihydro-2H-pyrido[3,2-b][1,4]oxazine

Name: 3,4-Dihydro-2H-pyrido[3,2-b][1,4]oxazine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 20348-23-6
Cat. No. CS-0039841
Purity≥97%
MDL No.MFCD09025907

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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3,4-Dihydro-2H-pyrido[3,2-b][1,4]oxazine|CS-0039841

Structure of 20348-23-6

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Description

This heterocyclic scaffold features a fused pyridine-oxazine core with inherent stability and tunable reactivity. The saturated dihydropyridine ring enables selective functionalization, while the oxygen atom enhances polarity and solubility. This structure serves as a key building block in medicinal chemistry for accessing bioactive molecules through modular derivatization pathways.

Application

3,4-Dihydro-2H-pyrido[3,2-b][1,4]oxazine serves as a versatile heterocyclic scaffold in medicinal chemistry, enabling efficient construction of bioactive molecules through standard functionalization at the pyridine and oxazine rings. Its stability under routine reaction conditions and compatibility with common coupling and reduction protocols facilitate downstream derivatization. Functions as a key building block for CNS-targeted compounds and kinase inhibitors, offering predictable reactivity in transition-metal-catalyzed transformations.

General Information

CAS No. 20348-23-6
Cat. No. CS-0039841
Purity ≥97%
MDL No. MFCD09025907
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₈N₂O
Molecular Weight 136.15
Synonym(s) None
SMILES C12=CC=CN=C1NCCO2

Computational Chemistry Data

TPSA 34.15
LogP 0.8859
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 0

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Morpholine compounds

Key Words

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3,4-Dihydro-2H-pyrido[3,2-b][1,4]oxazine

CAS No. 20348-23-6

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