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Structure of 20357-24-8
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5-Methoxy-2-nitrobenzaldehyde features a para-nitro group and a methoxy substituent positioned ortho to the aldehyde functionality, creating a strongly electron-deficient aromatic ring. This combination enhances reactivity in nucleophilic addition and condensation reactions, particularly in the synthesis of heterocycles and conjugated systems. The bench-stable aldehyde resists oxidation under standard conditions and integrates readily into multi-step synthetic sequences requiring precise electronic tuning.
5-Methoxy-2-nitrobenzaldehyde serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted heterocycles and bioactive scaffolds. Its ortho-nitro and para-methoxy groups provide complementary reactivity for sequential functionalization, while the aldehyde functionality facilitates condensation reactions, imine formation, and coupling protocols. The compound exhibits good bench stability and is compatible with standard purification techniques, making it suitable for use in medicinal chemistry campaigns and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: