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Structure of 2044711-52-4
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(R)-Fmoc-2-amino-4,4,4-trifluoro-butyric acid features a trifluoromethyl group that enhances metabolic stability and lipophilicity, ideal for peptide synthesis. The Fmoc protecting group enables efficient stepwise chain elongation under standard conditions, while the chiral (R)-configuration ensures stereochemical fidelity in target sequences.
(R)-Fmoc-2-amino-4,4,4-trifluoro-butyric acid serves as a valuable building block in peptide synthesis, enabling the incorporation of fluorinated amino acid motifs with enhanced metabolic stability. The trifluoromethyl group imparts increased lipophilicity and resistance to enzymatic degradation, while the Fmoc group provides orthogonal protection for amine functionality. This compound facilitates efficient coupling reactions under standard conditions, offers good bench stability, and simplifies purification due to its distinct polarity profile—making it well-suited for medicinal chemistry campaigns targeting bioactive peptides and peptidomimetics.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: