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Structure of 2055353-75-6
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Mal-amido-PEG3-acid is a bifunctional linker featuring a maleimide group conjugated to a PEG3 spacer terminated with a carboxylic acid. This design enables site-specific bioconjugation via thiol-Michael addition, while the hydrophilic PEG chain enhances solubility and reduces non-specific binding. The terminal carboxyl group facilitates further coupling reactions under standard activation conditions.
Mal-amido-PEG3-acid serves as a versatile, water-soluble bifunctional linker for conjugation workflows. The maleimide group enables site-specific thiol-Click coupling under physiological conditions, while the PEG3 spacer provides enhanced solubility and reduced non-specific binding. The terminal carboxylic acid facilitates amide coupling with primary amines, enabling efficient construction of dual-functional bioconjugates. Bench-stable and compatible with standard purification methods, it supports robust synthesis of antibody-drug conjugates, peptide-protein hybrids, and targeted delivery systems.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362+P364
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Lot numbers can be found on the outside label of a product: