Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-(tert-Butoxycarbonyl)benzoic acid

  • CAS No. 20576-82-3

  • Cat. No. CS-W005067
  • Purity≥96%
  • MDL No.MFCD04037901

*For research and further manufacturing use only, not for direct human use.

4-(tert-Butoxycarbonyl)benzoic acid|CS-W005067

Structure of 20576-82-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 20576-82-3
  • Cat. No. CS-W005067
  • Purity ≥96%
  • MDL No. MFCD04037901
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₄O₄
  • Molecular Weight 222.24
  • Synonym(s) 1,4-Benzenedicarboxylic acid, mono(1,1-dimethylethyl) ester
  • SMILES CC(C)(C)OC(=O)C1=CC=C(C=C1)C(O)=O

Description

4-(tert-Butoxycarbonyl)benzoic acid features a protected carboxylic acid group flanked by an electron-rich aromatic ring, enabling selective derivatization in peptide synthesis and medicinal chemistry. The tert-butoxycarbonyl moiety offers excellent stability under basic conditions and can be removed cleanly with trifluoroacetic acid. This compound integrates readily into complex molecular architectures with minimal side reactivity.

Synthesis

  • Route1
    • Di-tert-butyl terephthalate|CS-0154848
      28313-42-0
    • ~93%
    • In-stock
      4-(tert-Butoxycarbonyl)benzoic acid|CS-W005067
      20576-82-3

    References

    • Boehringer Ingelheim Pharmaceuticals, Inc. Patent: US5232928 A1, 1993 ; US 5232928 A
  • Route2

    References

    • Adlington; Baldwin; Becker; Chen; Cheng; Cooper; Hermann; Howe; McCoull; McNulty; Neubauer; Pritchard Journal of Medicinal Chemistry, 2001 , vol. 44, # 10 p. 1491 - 1508
  • Route3
    • In-stock
      Terephthalic acid|CS-W010814
      100-21-0
    • null|null
      75-65-0
    • ~39%
    • In-stock
      4-(tert-Butoxycarbonyl)benzoic acid|CS-W005067
      20576-82-3

    References

    • Mineno, Tomoko; Ueno, Tasuku; Urano, Yasuteru; Kojima, Hirotatsu; Nagano, Tetsuo Organic Letters, 2006 , vol. 8, # 26 p. 5963 - 5966

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   63.6
  • LogP   2.3401
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4-(tert-Butoxycarbonyl)benzoic acid sigma4-(tert-Butoxycarbonyl)benzoic acid manufacturer4-(tert-Butoxycarbonyl)benzoic acid price4-(tert-Butoxycarbonyl)benzoic acid structure4-(tert-Butoxycarbonyl)benzoic acid SDSbuy 4-(tert-Butoxycarbonyl)benzoic acid4-(tert-Butoxycarbonyl)benzoic acid supplier4-(tert-Butoxycarbonyl)benzoic acid uses4-(tert-Butoxycarbonyl)benzoic acid molecular weightprice of 4-(tert-Butoxycarbonyl)benzoic acid4-(tert-Butoxycarbonyl)benzoic acid chemical name formula of 4-(tert-Butoxycarbonyl)benzoic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label