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Structure of 205865-67-4
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Ethyl trimethylsilyldifluoroacetate features a stabilizing trimethylsilyl group that enhances handling and shelf stability. This reagent integrates readily into fluorinated building blocks, enabling efficient access to difluoromethylated synthons under mild reaction conditions.
Ethyl trimethylsilyldifluoroacetate serves as a stable, bench-ready synthon for introducing difluoromethyl groups into complex molecules. It functions as a versatile building block in nucleophilic fluorination and C–H functionalization reactions, enabling efficient access to fluorinated carbonyl derivatives and heterocyclic scaffolds. The trimethylsilyl group enhances stability and facilitates purification, while the ester moiety supports downstream transformations in medicinal chemistry and agrochemical synthesis.
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GHS Pictogram :
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GHS No : GHS02,GHS05,GHS07
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Signal Word : Danger
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UN#: 2924
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Class : 3,8
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Packing Group : Ⅱ
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Hazard Statements : H225-H315-H318-H335
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Precautionary Statements : P210-P240-P241-P280-P370+P378
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Lot numbers can be found on the outside label of a product: