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CS-W001157 4
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Tetrahydro-2H-pyran-4-ol

  • CAS No. 2081-44-9

  • Cat. No. CS-W004264
  • Purity≥98%
  • MDL No.MFCD00006633

*For research and further manufacturing use only, not for direct human use.

Tetrahydro-2H-pyran-4-ol|CS-W004264

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General Information

  • CAS No. 2081-44-9
  • Cat. No. CS-W004264
  • Purity ≥98%
  • MDL No. MFCD00006633
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₀O₂
  • Molecular Weight 102.13
  • Synonym(s) Tetrahydro-4-pyranol
  • SMILES OC1CCOCC1

Description

Tetrahydro-4-pyranol (4-Hydroxytetrahydropyran) was used in the quantitative analysis of 3-hydroxytetrahydropyran (3-HTHP).

Application

Tetrahydro-2H-pyran-4-ol serves as a versatile synthetic building block, offering a hydroxyl group at the C4 position of a stable tetrahydropyran ring. Its bench-stable nature and compatibility with standard protecting group manipulations enable reliable use in carbohydrate chemistry and medicinal compound synthesis. The molecule facilitates regioselective functionalization and acts as a key scaffold for heterocyclic systems requiring oxygenated cyclic frameworks.

Synthesis

  • Route1

    References

    • XCOVERY, INC. Patent: WO2008/88881 A1, 2008 ; Location in patent: Page/Page column 39 ; WO 2008/088881 A1
  • Route2
    • null|null
      110-88-3
    • null|null
      627-27-0
    • ~85%
    • In-stock
      Tetrahydro-2H-pyran-4-ol|CS-W004264
      2081-44-9

    References

    • Ube Industries, Ltd. Patent: EP1533307 A1, 2005 ; Location in patent: Page/Page column 5 ;
  • Route3

    References

    • Pehlivan, Leyla; Metay, Estelle; Delbrayelle, Dominique; Mignani, Gerard; Lemaire, Marc European Journal of Organic Chemistry, 2012 , # 25 p. 4689 - 4693

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1760
Class : 8
Packing Group : Ⅲ
Hazard Statements : H318
Precautionary Statements : P280-P305+P351+P338-P310

Quality Control

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Computational Chemistry Data

  • TPSA   29.46
  • LogP   0.1577
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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