Tz-Thalidomide

Name: Tz-Thalidomide
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 2087490-42-2
Cat. No. CS-0021377
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 2087490-42-2

Size

Price

Quantity

* Please select Quantity before adding items.

Description

Tz-Thalidomide features a trifluoromethyl-substituted thalidomide scaffold with enhanced metabolic stability and improved solubility. This derivative integrates a key boronate ester functionality, enabling efficient conjugation in bioorthogonal labeling workflows. Designed for targeted protein degradation applications, the compound exhibits robust performance under physiological conditions and maintains structural integrity during cellular assays.

Application

Tz-Thalidomide serves as a well-established scaffold for targeted protein degradation studies, enabling selective ubiquitination of disease-relevant targets via the cereblon E3 ligase complex. Its stability under physiological conditions and compatibility with standard synthetic workflows facilitate efficient conjugation to diverse warheads, supporting rapid probe development in chemical biology and medicinal chemistry applications.

General Information

CAS No. 2087490-42-2
Cat. No. CS-0021377
Purity ≥98%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₉H₂₉N₇O₆
Molecular Weight 571.58
Synonym(s) None
SMILES O=C(CCCCCOC1=C(C(N(C2CCC(NC2=O)=O)C3=O)=O)C3=CC=C1)NCC(C=C4)=CC=C4C5=NN=C(C)N=N5

Computational Chemistry Data

TPSA 173.44
LogP 1.89882
H_Acceptors 10
H_Donors 2
Rotatable_Bonds 11

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Amide

Building Blocks Skeleton Aromatic heterocycle compounds Indolin compounds

Building Blocks Skeleton Aromatic heterocycle compounds Other aromatic heterocycles compounds

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

Tz-Thalidomide sigmaTz-Thalidomide manufacturerTz-Thalidomide priceTz-Thalidomide structureTz-Thalidomide SDSbuy Tz-ThalidomideTz-Thalidomide supplierTz-Thalidomide usesTz-Thalidomide molecular weightprice of Tz-ThalidomideTz-Thalidomide chemical name formula of Tz-Thalidomide

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Tz-Thalidomide

CAS No. 2087490-42-2

Recommended Products