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Structure of 2089649-86-3
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3-Methyl-3,6-diazabicyclo[3.1.1]heptane dihydrochloride is a sterically hindered, bench-stable nitrogen heterocycle featuring two basic nitrogen centers in a rigid bicyclic framework. This structure enables efficient coordination in catalytic systems and enhances solubility in polar solvents. The compound serves as a robust ligand scaffold in transition metal catalysis and as a synthetic intermediate for functionalized heterocycles.
3-Methyl-3,6-diazabicyclo[3.1.1]heptane dihydrochloride serves as a rigid, sterically constrained bis(amine) scaffold with enhanced basicity and improved solubility compared to simpler aliphatic diamines. It functions effectively in transition-metal catalysis, particularly in ligand design for palladium-catalyzed cross-coupling reactions, where its nitrogen geometry supports stable complex formation. The dihydrochloride salt enhances bench stability and facilitates handling in aqueous or polar media, enabling efficient incorporation into modular synthetic routes for bioactive heterocycles and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS02
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Signal Word : Danger
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UN#: 1325
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Class : 4.1
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Packing Group : Ⅲ
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Hazard Statements : H228
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Precautionary Statements : P210-P240-P241-P280-P370+P378
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Lot numbers can be found on the outside label of a product: