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Structure of 209003-46-3
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4-Bromoquinoline-2-carboxylic acid features a bromine substituent at the 4-position and a carboxylic acid group at the 2-position of the quinoline scaffold. This combination enables direct functionalization in cross-coupling reactions and facilitates conjugation to biomolecules or polymer backbones via amide bond formation. The electron-deficient quinoline core enhances reactivity in transition metal-catalyzed transformations, while the bench-stable carboxylic acid serves as a reliable handle for derivatization under standard conditions.
4-Bromoquinoline-2-carboxylic acid serves as a versatile building block for constructing quinoline-based heterocycles and bioactive scaffolds. The bromine at the 4-position enables palladium-catalyzed cross-coupling reactions, while the carboxylic acid group facilitates amide bond formation, esterification, or direct derivatization. Its bench-stable crystalline nature and compatibility with standard synthetic workflows make it ideal for medicinal chemistry campaigns and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: