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Structure of 2091272-22-7
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5-Bromo-6-fluoro-2-methyl-2H-indazole is a halogenated indazole scaffold featuring complementary bromo and fluoro substituents at adjacent positions, enhancing electronic modulation and metabolic stability. The methyl group at the 2-position provides steric protection and improves solubility. This compound serves as a key building block in medicinal chemistry for targeted kinase inhibitors and bioactive heterocycles.
5-Bromo-6-fluoro-2-methyl-2H-indazole serves as a versatile building block for the synthesis of bioactive heterocycles, enabling efficient late-stage functionalization via palladium-catalyzed cross-coupling. The ortho-halogen substitution pattern facilitates selective derivatization, while the methyl group provides a handle for oxidation or further substitution. Its bench-stable nature and compatibility with diverse reaction conditions make it ideal for medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: