2-(3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-oxopiperidin-1-yl)acetic acid

Name: 2-(3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-oxopiperidin-1-yl)acetic acid
Brand: ChemScene
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CAS No. 209163-25-7
Cat. No. CS-0163656
Purity≥98%
MDL No.MFCD03414134

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2-(3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-oxopiperidin-1-yl)acetic acid|CS-0163656

Structure of 209163-25-7

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Description

This fluorenylmethoxycarbonyl-protected piperidine derivative features a reactive acetic acid handle for conjugation, enabling efficient incorporation into peptide chains. The Cbz-stabilized piperidinone scaffold enhances solubility and stability during synthetic workflows.

Application

2-(3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-oxopiperidin-1-yl)acetic acid serves as a versatile building block for peptide synthesis, enabling efficient incorporation of piperidine-derived motifs into bioactive scaffolds. The Fmoc-protected amine and carboxylic acid functionalities offer orthogonal reactivity, facilitating coupling reactions under standard conditions. Its bench-stable nature and clean purification profile support reliable use in solid-phase and solution-phase workflows.

General Information

CAS No. 209163-25-7
Cat. No. CS-0163656
Purity ≥98%
MDL No. MFCD03414134
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₂H₂₂N₂O₅
Molecular Weight 394.42
Synonym(s) Fmoc-3-1-carboxymethyl-2-valerolactame
SMILES O=C(O)CN1C(C(NC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O)CCC1)=O

Computational Chemistry Data

TPSA 95.94
LogP 2.6007
H_Acceptors 4
H_Donors 2
Rotatable_Bonds 5

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Other Classifications

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Key Words

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2-(3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-oxopiperidin-1-yl)acetic acid

CAS No. 209163-25-7

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