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Structure of 209252-17-5
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Fmoc-β-HoAsp(OtBu)-OH is a protected aspartic acid derivative featuring a β-hydroxy side chain and a tert-butyl ester group, enabling selective incorporation into peptide sequences. This moiety delivers enhanced solubility and stability under standard coupling conditions, facilitating efficient solid-phase synthesis of complex peptides with hydroxylated residues.
Fmoc-β-HoAsp(OtBu)-OH serves as a key building block for the synthesis of peptide libraries and cyclic peptides, enabling site-specific incorporation of β-hydroxyaspartic acid residues. The Fmoc group provides efficient orthogonal protection for amine functionality, while the OtBu ester offers stable yet cleavable carboxyl protection under standard conditions. This derivative exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for solid-phase peptide synthesis and the construction of complex bioactive scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: