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Structure of 2096331-60-9
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3-Nitro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine features a boronate ester group paired with an electron-deficient pyridine ring, enabling efficient Suzuki-Miyaura coupling under standard conditions. This bench-stable reagent integrates readily into complex molecule assembly, offering reliable functionalization at the 5-position.
3-Nitro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The nitropyridine motif provides enhanced electrophilicity and facilitates downstream functionalization, while the tetramethylboronate group ensures excellent stability, low toxicity, and compatibility with aqueous workups. Its orthogonality to common functional groups enables efficient late-stage diversification in heterocyclic synthesis, making it a reliable scaffold for medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: